AB1632 PREVALENCE OF PATIENTS WITH SYSTEMIC LUPUS ERYTHEMATOSUS AT THE REFERRAL CENTERS IN ITALY: A MULTICENTER STUDY

Background Systemic lupus erythematosus (SLE) is an autoimmune disease mostly affecting the young women during their third-fourth decade of life. SLE characterized by variable manifestations and, potentially, every organ can be involved. The course and complexity disease, naturally appeal to manage patients with at high qualified national referral centers. [1] Despite relevant burden associated both from patient physician point view, epidemiological data on in Italy are limited isolated estimates, captured different sources [2-5]; however, no larger prevalence centers available date. Objectives This study aimed estimating tertiary Italian centers, representative scenario. Methods We conducted observational, cross-sectional followed district, North, Centre, South Isles (Brescia, Padua, Udine, Ferrara, Florence, Pisa, Rome, Bari, Naples, Cagliari). Data sexes any age, fulfilling 2019 ACR/EULAR classification criteria, were obtained hospital medicals records. To estimate prevalence, we reported number referring considered (numerator), over total population resident included districts (denominator), according National Statistical Institute (ISTAT), responsible for general censuses. For analysis, only complete sent January 13th, 2023. [7] Results identified 3251 n° 9 this study. 1163/3251 (89.3%) female, 1302/3251 (40%) residing estimated overall was 21.37 cases per 100,000 individuals. As stratified results geographical area (North, Islands) Italy, ranged 14.7 27.1 ( Table 1 ) Conclusion Our multiple These preliminary show first time proportion attending suggesting a distribution diverse areas country. References [1]Tsokos, N Engl J Med 2011 [2]Benucci, Sci Monit 2005 [3]Govoni, Lupus 2006 [4]Tsioni, Clin Exp Rheumatol 2015 [5]Zen, Rheumatology 2022 [6]Aringer, Arthritis http://dati.istat.it/ 1. North Center Overall Number involved 1728 827 696 Patients district (%) 824 (47.7%) 230 (27.8%) 272 (39.1%) 1302 female 734 (89.1%) 183 (88.8%) 246 (90.4%) 1163 Prevalence (cases individuals) 16.4 16.5 21.8 Acknowledgements acknowledge Dr Ettore Silvagni, Sebastiano Lorusso, Augusta Ortolan, Sara Ferrigno, Marcella Prete, Fabio Congiu help collection. Disclosure Interests None Declared.